Chelsea v Roma
Chelsea manager Luiz Felipe Scolari could hand Deco his first start since mid-September when his side host Roma in the Champions League on Wednesday.
The Portuguese midfielder missed five matches with a torn thigh muscle while goalkeeper Petr Cech also (thigh) and midfielder Joe Cole could also return.
Roma welcome back defenders Philippe Mexes and Christian Panucci after serving domestic suspensions.
Captain Francesco Totti should start having recovered from knee surgery.
Totti made his first start since April against Inter Milan on Sunday, playing 69 minutes before being replaced by Jeremy Menez.
"I'm satisfied, even though I'm still not 100%," he said. "I think I'll play against Chelsea."
Chelsea's Ashley Cole and Didier Drogba are both nearing comebacks after injury but are unlikely to feature against Roma.
Scolari is still without Michael Ballack, Michael Essien and Ricardo Carvalho but their replacements have fitted seamlessly into the side.
Sitting top of the Premier League with six wins and two draws from eight matches and a goal difference of +16, Chelsea's form contrasts sharply with that of Roma.
The Italians are 14th in Serie A with two wins and four defeats from seven games and a goal difference of -4 following their 4-0 home defeat by Inter.
"I enjoy watching my team but I am more happy when we win," said Scolari. "It's a pleasure, not only for me, but for the players that people like Chelsea football.
"We play beautiful football. But if we need three points in every game, sometimes it is impossible to play beautiful football.
"You will see a beautiful game against Roma because they play like Chelsea."
Luciano Spalletti's men suffered a shock 2-1 home defeat by Cluj in their opening Group A match but bounced back with an impressive 3-1 win against Bordeaux.
Chelsea beat Bordeaux 4-0 at home before being held to a goalless draw by Cluj in Romania.
Victory would move the London club to the brink of qualification for the knockout rounds, while defeat for Roma would leave them four points off the summit of Group A at the half-way point.
"We need to win tomorrow to qualify," Scolari added. "If we win, we'll have 50% or 70% of the qualification achieved.
"After we play Roma again, then Bordeaux. The last game will be at home (against Cluj). The most important game for us is tomorrow as, afterwards, if we draw or win one more game, we are in the second stage."
Chelsea (from): Cech, Hilario, Cudicini, Ivanovic, Ferreira, Malouda, Obi, Deco, Kalou, Bosingwa, Terry, Lampard, Anelka, Belletti, Alex, Carvalho, Mancienne, Bridge, Di Santo, J Cole.
